The Oral Health Status in Oncopatients after COVID 19: Literature Review

Tamuna Dundua, Vladimer Margvelashvili


Background: Cancer patients are under higher risk in all criteria, as for their immunosuppressed status due to anticancer treatment becomes more immunosuppressed and oral health for them is unconditionally important, as for by a new definition of oral health by FDI - World Dental Federation, oral health is strongly related to overall health and well-being. Based on reviewed literature, the evolution of the oral lesions and the healing process occurs at the same time with COVID-19 infection. Presence of multiple oral manifestations leads us to suppose that the development of oral manifestations in patients may be directly are associated with the COVID-19 infection, moreover there is an evidence about the major receptor for the SARS-CoV-2 virus - Angiotensin-Converting Enzyme 2 (ACE2) presenting in the epithlium of the salivary glands and gingiva.

Aim: The aim of the study is to review and summarize published literature on oral health manifestations and cancer patients related to SARS-CoV-19.

Methods: Based on literature in the databases Scopus, PubMed and ScienceDirect with terms “Oral Health”, “Cancer Patients”, “Covid 19” in the title, abstract and keywords, we gathered up to dated information between 2020-2021 about Covid 19 and cancer patients and their Oral Health Status during Covid 19.

Results: Totally 60 articles were identified from searching mentioned databases, 22 were picked out for this review considering in most of relevance to topic of review. The triad xerostomia, taste dysfunction, aphtous ulcer, erithema and mucormycosis are common oral manifestations presented on unspecified oral mucosal sites (25.3%), tongue (15.03%), unspecified lips (6.25%), palate (4.7), labial commissure (3.9%), and lower lip (2.9%).

Conclusion: The obtained material shows that in the coexistence of immunosuppressive condition and / or chronic disease, numerous cases of mild manifestations have been described, and vice versa, on the basis of which we can assume that in-depth analysis we will gain extensive knowledge in the treatment of complicated covariate patients. There is no sufficient evidence to declare the lesions are caused directly by the virus or is an associated manifestation resulting from the severe compromised state of the patient, especially cancer patients.  Further researches are needed to determine the Oral Health Status in oncopatients (Oncologic patients) after Covid 19 for improving their oral and overall well-being.


Oral Health, COVID-19, Global Health, Cancer Patients


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