TRANSLATIONAL AND CLINICAL MEDICINE - Georgian Medical Journal

Introduction: Improving the results of hernia treatment and prevention of complications became a goal of our research which in­cluded two parts – experimental and clinical. Histomor­phological and bacteriological researches showed that the best result out of the 3 control groups was received in case of covering implant “Coladerm”+ with chlorhexidine.

Based on the experiment results working process con­tinued in clinics in order to test and introduce new “co­laderm”+ chlorhexidine covered poliprophilene meshes into practice.

Materials and Methods: For clinical illustration there were 110 pa­tients introduced to the research who had hernioplasty procedures by different nets: I group – standard meshes+”coladerm”+chlorhexidine, 45 patients; II group - standard meshes +”coladerm”, 35 patients; III group – standard meshes, 30 patients. Assessment of the wound and echo-control was done post-surgery on the 8th, 30th and 60th days.

Results: This clinical research based on the experimental results once again showed the best anti-microbe features of new antiseptic polymeric biocomposite meshes (stan­dard meshes+”coladerm”+chlorhexidine); timely termi­nation of regeneration and reparation processes without any post-surgery suppurative complications.

Conclusion: We hope that new antiseptic polymeric biocomposite meshes present­ed by us will be successfully used in surgical practice of hernia treatment based on and supported by experimental-clinical research

hernia; antiseptic mesh; “coladerm”+ chlorhexidine covered poliprophilene meshes

Markov G. Some contemporary aspect in the preventions of the surgical site infections OK Hirurgia. Sofia: 2007; 1-2: 54-9.

Yorke Y, McDeavitt K, Martin A, lincourt E, Vertegel A, Heniford T. Mesh Nevel Techniqve involving naturally ocurrrin cellular proteins. Carolinas medical Center. Char¬lotte. NC. USA Surg Innov. 2011; 7: 4-8.

Gullaume O., Lavigne J.P., Lefrane O., Nottelet B., Caudane J., Garric X. New antibiotic eliting mesh used for tissue reinforcement Acta Biomater. 2011; 7(9):3390-7.

Gogoladze M., Chkhikvadze T., Kiladze M., Jikia D. Georgia. Current issues,problems and prosthetics of tension-free hernioplasty (Review) „Georgian MedicalNews“, 2014, №7-8 (232-233), pp. 7-12.

Gogoladze M., Kiladze M., Chkhikvadze T., Tsivtsivadze L, Jiqia D. ;Georgia Hernioplastic morphological features (experimental stady).. „Georgian Medical News“, 2016, №5 (254), pp. 73-81.

Gogoladze M., Chkhikvadze T., Kiladze M., Jikia D. 1, Georgia . Bacteriological description of ,,new’’aseptic meshes (Experimental stady). ,, Experimental & Clinicl MEDICINE,, 2016, N5; pp. 36-41.

Gogoladze M., Kiladze M., Chkhikvadze T., Jiqia D., Georgia. Clinical evaluation of the new antiseptic meshes, „Georgian Medical News“, 2016, №12 (261), pp. 7-11.