Aneurysmal Bone Cyst of Pelvic Bones – patient wrestler (case report)

David Makaridze, Liana Gogiashvili, Tamuna Gvianishvili, George Loria

Abstract


Aneurysmal Bone Cyst (ABC), given its etiology and pathogenesis, remains one of the most controversial topics in orthopedics. Complications associated with ABC are not rare and can significantly impact professional or physical activities. We present a case of ABC-like changes (2020) with polyostotic variants in an 18-year-old male patient who is a professional wrestler.

The pelvic area exhibited ABC-like changes affecting two bones – the right pubic ramus and sacrum, characterized by multiple fluid-fluid or blood-fluid cysts and tumor complications including osteolysis and necrosis. Preoperative MRI imaging, histopathological examination, and special immunohistochemical reactions (CD68, p63, Ki67) conducted on operative materials confirmed a transformation of Giant Cell Tumor of Bone into an ABC. The expression of the P63 transcription protein is crucial as it suggests a lower potential for malignancy in the affected area.

Extensive curettage of the lesion and grafting with 'ZimmerBionet Gentamicin Bone Cement' were performed without fixation of the hemipelvis. Long-term outcomes and the patient's return to athletic activities support a benign prognosis.


Keywords


Pelvic area disorders; Aneurysmal bone cyst; Giant cell bone tumor.

Full Text:

PDF

References


WHO Classification of Tumours Editorial Board. Soft tissue and bone tumours. International Agency for Research on Cancer. 2020

Rosenberg AE, Nielsen GP, Fletcher JA. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; 2002. Aneurysmal bone cyst.

Deventer N, Deventer N, Gosheger G, de Vaal M, Vogt B, Budny T. Current strategies for the treatment of solitary and aneurysmal bone cysts: a review of the literature. J Bone Oncol. 2021; 20:30:100384. doi: 10.1016/j.jbo.2021.100384.

Thomas P G van Geloven, Michiel A J van de Sande, Lizz van der Heijden. The treatment of aneurysmal bone cysts. CurrOpinPediatr. 2023;35(1):131-137. doi:10.1097/MOP.0000000000001205.

David Makaridze, Liana Gogiashvili1, Armaz Mariamidze, George Loria, Tamuna Gvianishvili, Lali Bekauri. Diagnostic Accuracy of Aneurysmal Bone Cyst (ABC): Immunohistochemical Aspects. Recent Advances in Clinical Trials. 2023; 3(4):1-6.

Howard Y Park, Sara K Yang, William L Sheppard, Vishal Hegde, Stephen D Zoller, Scott D Nelson, Noah Federman, Nicholas M Bernthal. Current management of aneurysmal bone cysts. Curr Rev Musculoskelet Med. 2016;9(4):435-444. doi: 10.1007/s12178-016-9371-6.

Restrepo R, Zahrah D, Pelaez L, Temple HT, Murakami JW. Update on aneurysmal bone cyst: pathophysiology, histology, imaging and treatment. PediatrRadiol. 2022;52:1601–1614. doi: 10.1007/s00247-022-05396-6.

Vincenzo Graziano, Vincenzo De Laurenzi. Role of p63 in cancer development. BiochimBiophys Acta. 2011;1816(1):57-66. doi: 10.1016/j.bbcan.2011.04.002.

Nawal Hammas, Chbani Laila, Alaoui Lamrani My Youssef, El Fatemi Hind, TaoufiqHarmouch, TiznitiSiham, AmartiAfaf. Can p63 serve as a biomarker for giant cell tumor of bone? A Moroccan experience. Diagn Pathol. 2012:7:130. doi: 10.1186/1746-1596-7-130.

Mohd Said Dawod, Mohammed S Alisi, Hammam Rabab’a, Ahmed A Abdulelah, Huthaifa W Almaaitah, Bassem Haddad. Surgical Management of Aneurysmal Bone Cyst of the Pubis: A Case Report and Review of Literature. International Medical Case Reports Journal. 2022; 15: 287–292. doi: 10.2147/IMCRJ.S369073

Rao A, Samant PD, Varshneya A. Aneurysmal bone cyst of pubic ramus: a rare entity. J Orthop Case Rep. 2013;3(4):42–45. doi: 10.13107/jocr.2250-0685.131

Khalid A Bakarman. Diagnosis and Current Treatment of Aneurysmal Bone Cysts. Cureus. 2024; 16(2): e53587. doi: 10.7759/cureus.53587

Martinez V, Sissons HA. Aneurysmal bone cyst. A review of 123 cases including primary lesions and those secondary to other bone pathology. Cancer. 1988;61:2291–2304. doi: 10.1002/1097-0142(19880601)61:11<2291::aid-cncr2820611125>3.0.co;2-v.

Doriana Di Costa, Elena Gabrielli, Mariagrazia Cerrone, Emidio Di Gialleonardo, Giulio Maccauro, Raffaele Vitiello. Pathological Fractures in Aneurysmal Bone Cysts: A Systematic Review. J Clin Med. 2024;13(9):2485. doi: 10.3390/jcm13092485.

Elham Nasri 1, John David Reith. Aneurysmal bone cyst: a review. J Pathol Transl Med. 2023;57(2):81-87. doi: 10.4132/jptm.2023.02.23.

E Mascard, A Gomez-Brouchet, K Lambot. Bone cysts: unicameral and aneurysmal bone cyst. Orthop Traumatol Surg Res. 2015;101(1 Suppl):S119-27.

Khan AQ, Siddiqui YS, Parameshwar A, Anwar-Sherwani MK. Aneurysmal bone cyst of ‎pubis. A rare presentation. Saudi Med J. 2010;31(3):317–320.

Ashok Nayak, Shreepad Kulkarni, Avinash Kulkarni, K. Natesh, Monish Bami. Aneurysmal Bone Cyst of the Pubis: A Case Report. J Clin Diagn Res. 2013; 7(8): 1740–1742. doi: 10.7860/JCDR/2013/5514.3254

Downey C, Daly A, Molloy AP, O’Daly BJ. Atraumatic groin pain secondary to an ‎aneurysmal bone cyst: a case report and literature review. World J Orthop. 2020;11(3):197–205. doi: 10.5312/wjo.v11.i3.197


Refbacks

  • There are currently no refbacks.




 

Become a REVIEWER 

 

ISSN: 2346-8491 (online)

slot88

slot777

https://iasjournals.org/

https://www.ejournal.spdfharmony.com/