Insulin like growth factor 1 dependence in patients with metabolic syndrome of nodular pathology of the thyroid gland

Meri Rekvava, Lali Javashvili, Elene Giorgadze

Abstract


Metabolic syndrome and nodular pathology of the thyroid gland is a widespread problem nowadays. Recently there has been a notable coincidence between metabolic syndrome and nodular pathology of thyroid gland. Hence, it is interesting to reveal the possible pathogenetic connection between these two diseases.
During the reviewing of articles in the Pubmed and Google Scholar database, the attention was attracted on the insulin-like growth factor system, which activates the cell growth and proliferation. Insulin-like growth factor system is activated during hyperinsulinemia, which alongside with insulin resistance and obesity forms basis for the development of metabolic syndrome.
Consequently, formed an idea to reveal the correlation between IGF 1 and thyroid nodular disease  in patients with metabolic syndrome.

Keywords


Metabolic syndrome; Insulin like Growth Factor 1; Thyroid gland

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