Alveolar Ridge Split And Augmentation Using Recombinant Human Bone Morphogenic Protein (rh-BMP-2) And Inorganic Xenograft

Teimuraz Ebanoidze, Ketevan Chichua, Sopio Samkharadze, Marika Zurmukhtashvili, Irakli Ebanoidze

Abstract


The initial stage of restoration of missing teeth and, accordingly, their functional or aesthetic value, is dental implantation, which requires adequate volume (at least 10mm height and 6 mm – width) and quality of surrounding bone tissue. In case of its deficiency, different methods of bone augmentation are used, among which is the splitting of the alveolar ridge. Its indication is the presence of a narrow alveolar ridge (less than 6 mm, but not less than 3 mm). The bony ridge is divided into buccal and lingual plates with a piezoelectric instrument; An implant is placed between them together with a bone graft. The graft with its osteoconductive properties, represented by an inorganic components - hydroxyapatite and tricalcium phosphate, is enriched with recombinant human bone morphogenic protein (rhBMP-2), giving the graft an osteoinductive character, i.e. Stimulates osteogenesis and accelerates bone consolidation. It is obtained by modifying the transfected gene of the Escherichia Coli. Granular graft together with bone morphogenic protein ensures full-fledged bone formation by maintaining own buccal and lingual (palatal) bone plates, which is the best condition for dental implant integration. The article will consider 2 clinical cases of alveolar ridge splitting, its augmentation and simultaneous dental implant placement.


Keywords


Alveolar ridge splitting, bone augmentation, Bone Morphogenic Protein, osteoinduction, osteoconduction, piezosurgery

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References


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