Gender differences in coronary collateral circulation during acute and stable ischemic heart disease

Maia Chigogidze, Nino Sharashidze, Zurab Paghava


Background:  Diseases of the cardiovascular system are seen in the wholeworld as the main cause of death. In women, heart attack and stroke are associated with twice increased mortality rate. Collateral blood vessels during the coronary artery disease represent an alternative source of myocardial blood circulation. They reduce the infarction area, improve the functioning of the heart , avoid  development of the ventricular aneurysm. The sex-related differences in patients with ischemic heart disease in relation to anatomy of coronary blood vessels have been estabished. However, the existence of gender differences in relation to the coronary collateral circulation and its determining factors is unknown.


Method:  We have used Pubmed and Google Schoolar medical databases and retrieved the articles for the last 10 years, containing the following keywords: Coronary artery deasease, Ishcaemic heart disease, Human coronary collateral circulation, Vasculogenesis, Angiogenesis, Gender differences in coronary colatteral circulation.


Conclusion:  There was not detected any credible research in terms of gender differences in coronary colatteral circulation,  which is a pressing issue and is still a subject of research, in   the scientific articles, searched for by us in Pub med and Google Scholar medical databases for 2006-2016.



Coronary artery deasease; Ishcaemic heart disease; Human coronary collateral circulation; Vasculogenesis; Angiogenesis; Gender differences in coronary colatteral circulation;

Full Text:



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